ngurel [at] mednet (dot) ucla (dot) edu
I am a postdoctoral researcher at David Geffen School of Medicine at UCLA, with Jeffrey Ardell at the UCLA Neurocardiology Research Center of Excellence/Cardiac Arrhythmia Center. I recently finished my Ph.D. in the School of Electrical and Computer Engineering at Georgia Tech. I worked with Omer T. Inan and I was a member of the Inan Research Lab.
My research revolves around two main themes: noninvasive sensing and neuromodulation. Particularly, I work in the intersection of biomedical instrumentation, signal processing, and machine learning with a focus on mood and performance improvement. I develop noninvasive tools and signal processing algorithms in the context of psychological stress and heart disease to improve their measurement, understanding, and management. My major focus is noninvasive vagus nerve stimulation for stress-related psychiatric disorders. Application areas are cyber-physical systems (CPS), smart and connected health (SCH), Internet of Things (IoT), and novel therapeutics. [longer bio]
News and Highlights
OCT 15, 2020 Another new paper in press! "Transcutaneous Cervical Vagal Nerve Stimulation Reduces Sympathetic Responses to Stress in Posttraumatic Stress Disorder: A Double-Blind, Randomized, Sham Controlled Trial", Neurobiology of Stress. [DOI]
OCT 15, 2020 New paper in press! "Effect of Transcutaneous Cervical Vagus Nerve Stimulation on the Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Response to Stress: A Randomized, Sham Controlled, Double Blind Pilot Study", Comprehensive Psychoneuroendocrinology. [DOI]
SEP 6, 2020 New review paper in press! "Application of Non-Invasive Vagal Nerve Stimulation to Stress-Related
Psychiatric Disorders", Journal of Personalized Medicine. [DOI]
AUG 26, 2020 New paper in press! "Transcutaneous Vagal Nerve Stimulation Blocks Stress-Induced Activation of Interleukin-6 and Interferon-γ in Posttraumatic Stress Disorder: A Double-Blind, Randomized, Sham-Controlled Trial", Brain, Behavior, Immunity - Health. [DOI]
AUG 12, 2020 I defended my PhD! Many thanks to family, friends, mentors, mentees, collaborators, patients, reviewers, everybody who supported me along the way.
JUL 28, 2020 My PhD Dissertation Defense "Novel Technologies for the Diagnosis and Treatment of Posttraumatic Stress Disorder" will take place on August 12th, 2PM ET. Feel free to join! [Details]
JUL 26, 2020 New paper in press! "Investigating Digital Cardiovascular Biomarker Responses to Transcutaneous Cervical Vagus Nerve Stimulation: State-Space Modeling, Prediction, and Simulation", JMIR mHealth and uHealth. [DOI]
JUN 6, 2020 New paper in press! "Non-Invasive Vagal Nerve Stimulation Decreases Brain Activity During Trauma Scripts", Brain Stimulation. [DOI]
MAY 20, 2020 I was a virtual guest for Turkey's Bahcesehir University Faculty of Medicine, we talked about post-COVID-19 health tech, streamed live. / [Turkish] Bugün Bahçeşehir Üniversitesi'nin COVID-19 ile ilgili online seminerinin konuğuydum. Youtube link [Turkish]: [COVID-19 Sonrası Sağlık Teknolojileri]
APR 3, 2020 Join us through Zoom for a session in NYC Neuromodulation Online 2020 Conference! You can register for the session "Noninvasive Vagus Nerve Stimulation Applied to Stress Management, Opioid Withdrawal, and Neurocognitive Disorders" (April 22, 12PM-2PM ET) via the conference website.
MAR 31, 2020 Congratulations to Asim Gazi for winning the NSF GRADUATE RESEARCH FELLOWSHIP!!!!
MAR 30, 2020 Doug got funding from the VA Merit Review Program to study nVNS in veterans with co-morbid mild Traumatic Brain Injury (mTBI) and PTSD based on the data we have on nVNS in PTSD so far! (PI: JD Bremner)
MAR 17, 2020 See our new paper: "Automatic Detection of Target Engagement in Transcutaneous Cervical Nerve Stimulation for Traumatic Stress Triggers", IEEE Journal of Biomedical and Health Informatics (IEEE JBHI). [DOI]
FEB 28, 2020 Check out our review article on PTSD: "Confederates in the Attic: Posttraumatic Stress Disorder, Cardiovascular Disease, and the Return of Soldier's Heart", The Journal of Nervous and Mental Disease. [DOI]
FEB 26, 2020 I am very excited to share that our Emory, Georgia Tech, and CUNY teams got funded with an NIH NIDA UG3/UH3 grant: "Noninvasive Vagal Nerve Stimulation in Patients with Opioid Use Disorders". UG3 Phase: $460k, UH3 Phase: $3.9M, PIs: JD Bremner, OT Inan.
DEC 1, 2019 Proud to be highlighted in the bi-annual IEEE Women in Engineering Magazine! Check out the article.
NOV 22, 2019 Presented at the National Institutes of Mental Health, Non-invasive Neuromodulation Unit.
OCT 22, 2019 Check out our Society for Neuroscience abstract!
OCT 2-5, 2019 Attending the Nexus NextProf Future Faculty Workshop at Georgia Tech.
AUG 27, 2019 Attending ECE Rush at Georgia Tech to talk about our research and what we do. New students, undecided folks, transfer students, come say hi!
AUG 8, 2019 New paper in press in Brain Stimulation! "Quantifying Acute Physiological Biomarkers of Transcutaneous Cervical Vagal Nerve Stimulation in the Context of Psychological Stress". [DOI]
AUG 1, 2019 AMIA's Maintenance of Certification (MOC) committee selected our paper to be certified as offering MOC-II credit to board-certified clinical informaticians. In other words, it was determined to be highly relevant to practicing clinical informaticians. They will be offered credit for learning about our work.
JUN 14, 2019 Our full paper on timing considerations for nVNS in clinical studies was accepted to AMIA 2019 Annual Symposium as oral presentation!
JUN 14-21, 2019 I will give two hands-on wearable electronics classes to 39 high school students of Georgia as a part of H.O.T. Days @ Georgia Tech Day Camp. Let the t-shirts glow!
JUN 6, 2019 New paper in press in The Journal of Nervous and Mental Disease! “Confederates in the Attic: Posttraumatic Stress Disorder, Cardiovascular Disease, and the Return of Soldier’s Heart”
MAY 22, 2019 Our poster presented and first authored by Asim Gazi got the Runner-up Best Poster Award at IEEE BHI!
MAY 19, 2019 We are presenting two posters at IEEE BHI & BSN in Chicago, IL!
MAY 8, 2019 New paper with Emory School of Medicine and Rollins School of Public Health: Comparison of autonomic stress reactivity in young healthy versus aging subjects with heart disease. [DOI]
APR 1-2, 2019 Co-organizing NSF/NIH Digital Clinical Trials Workshop on the NIH main campus, Bethesda, MD.
Day 1 VideoCast: [Digital Clinical Trials Workshop: Creating a Vision for the Future, Day 1]
Day 2 VideoCast: [Digital Clinical Trials Workshop: Creating a Vision for the Future, Day 2]
MAR 22, 2019 Attending iREDEFINE Workshop in conjunction with ECEDHA Conference in Tucson, AZ.
DEC 19, 2018 Georgia Tech featured our visit to MIT! [link]
OCT 1, 2018 New paper: Headband to classify mentally stressful tasks. [DOI]
Doug Bremner is giving a talk on our work "Non-invasive Vagal Nerve Stimulation Paired with Stress Exposure in PTSD".
JUL 17, 2018 Attending IEEE EMBC in Honolulu, HI. I will give a talk on our instrumented nest for heartbeat detection from rodents. Evaluated per reviewer feedback, I was selected Best Paper Finalist in Student Paper Competition -my paper is among Top 15 of the accepted ~1500 proceedings! [DOI] [link] [all finalists]
MAR 4, 2018 Attending IEEE BSN & BHI in Las Vegas, NV. I will give a talk on our noninvasive neuromodulation work in BSN. I received Runner-up Best Paper Award in BSN Best Paper Competition! [DOI] [news]
DEC 7, 2017 Our poster presented by Jeff won the Best Poster Award at NextFlex Flexible Hybrid Electronics Workshop! [news]